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Hillcrest Infusion Center

At Prisma Health Hillcrest Hospital Ambulatory Infusion Center, our highly trained care team provides personalized attention to each patient.

With easy scheduling and genuine hospitality, we reduce patient anxiety, and each of our infusion suites provides comfortable chairs with personal blankets, wifi and snacks.

Serving Simpsonville and the greater Upstate of South Carolina, our commitment to quality, individualized care and clinical excellence provides patients with a convenient, safe alternative for specialty drug infusion.

Our services

Some of the treatment therapies we offer include:

  • Remicade (for ulcerative colitis, Crohn’s disease, rheumatoid arthritis, psoriasis)
  • IV antibiotics and first dose monitoring
  • IV hydration
  • IV immune globulin (for immunodeficiency conditions)
  • Solumedrol
  • Osteoporosis medications
  • Iron replacement therapy
  • Blood products
  • Implanted port and PICC line maintenance, blood draws, and declot
  • PICC line insertion
  • Aranesp Injection (No Procrit available)
  • Rabies Vaccine (after initial dose in ER or Urgent Care)
  • Xolair injection
  • Nucala Injection
  • Ultrasound guided peripheral IV insertion
  • ACTH stimulation test

Infusion therapy guidelines

We recognize the unique needs of our infusion patients, and understand the desire to have family and friends present during treatments. However, there are times that visitors may be restricted at the discretion of our nursing staff. We will make every effort to be flexible with these guidelines.

  • Please, no perfume, colognes or fragrances.
  • Infusion times are highly specialized and individualized, running from 30 minutes to over six hours. Books, magazines, e-readers, crossword puzzles, word search games or Sudoku are welcome.
  • Free wifi is available. We respectfully ask that you mute or use earphones with all electronic devices like iPads, laptop computers, cell phones, electronic games and MP3 players, so they don’t disturb other patients.
  • Bring along handiwork such as knitting, crochet needlework, etc.
  • The Infusion Center is kept on the cool side to decrease the chance of infection. Wear comfortable clothing that is personally easy to adjust in case you become overly warm or cool.
  • Infusions are usually administered through an arm, so please wear clothing that is easy for the nurse to access.
  • Certain infusions may require that someone drive you home.
  • You may eat or drink as usual unless specific instructions are given.
  • Please take your daily medications as usual, especially blood pressure medications. Bring any home medications that you may need while you are receiving your infusion.

Contact Us

729 S.E. Main St.
Simpsonville, SC 29681
P: 864-454-6348
F: 864-454-6351


Monday-Friday 10 a.m. – 6 p.m., Saturday and Sunday are scheduled appointments for once daily antibiotics only.